Using "chromosome" in a sentence

BIOTECH Synthetic Bacteria Becomes Smallest Lifeform That Can Move Around Michael Irving | New Atlas “In 2010 scientists at JCVI unveiled the world’s first completely synthetic lifeform—a micro-organism derived from a synthetic chromosome made up of four chemicals and designed using a computer.
Source: Singularity Hub

Studies have credited Ethiopians and their great distance running rivals, the Kenyans, with ‘favourable somatotypical characteristics lending to exceptional biomechanical and metabolic economy/efficiency’, or examined the ‘Y chromosome haplogroup distribution’ of Ethiopian athletes.
Source: Runner's World

Suggestive associations for aTRH: LocusZoom plots (C–F) showing the suggestive associated SNPs on chromosome 1 (C), 4 (D), 5 (E), and 15 (F) from GWAS of aTRH, respectively.
Source: BMC Medicine BMC Medicine

Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons.
Source: Nature.com

These include chromosome microarray (CMA), targeted exome sequencing (TES), diagnostic exome sequencing (DES), full-length exome sequencing (WES), and diagnostic genome sequencing (DGS).
Source: KBR

Full size imageA chromosome-scale genome assemblyHere, we report a high-quality, chromosome-level genome assembly of Cycas panzhihuaensis based on sequencing of the haploid megagametophyte using a combination of MGI-SEQ short-read, Oxford Nanopore long-read and Hi-C sequencing methods (Supplementary Note 2).
Source: Nature.com

Now, researchers from the Okinawa Institute of Science and Technology (OIST), in collaboration with a number of other research institutes including K MIKIMOTO & CO, LTＤ, Pearl Research Institute and Japan Fisheries Research and Education Agency, have constructed a high-quality, chromosome-scale genome of pearl oysters, which they hope can be used to find resilient strains.
Source: The Fish Site

“Parts of the genome in many species have what we call a ‘genetic inversion,’ which means that the genes on the chromosome from one parent have a certain order and the genes on the same chromosome that come from the other parent that code for the same thing, and they’re the same area, but they’re flipped,” Baumann says.
Source: UConn Today University of Connecticut

Regional association plot at chromosome 15 demonstrates the prioritization of MFGE8 as the likely causal gene for rs1807214, which lies in an intergenic region of chromosome 15.
Source: Nature.com

(For comparison, a single human chromosome contains between 50 million and 260 million bases.
Source: The Daily Beast

However, for a given parent cell’s chromosome pair, drive is achieved when wtf4 is found only on one chromosome.
Source: EurekAlert

By Michael Le Page The Amami spiny ratASATO KUROIWA For any mammal, the loss of the Y chromosome should mean the loss of males and the demise of the species.
Source: New Scientist

Single-cell RNA-seq reveals lineage and X chromosome dynamics in human preimplantation embryos.
Source: Nature.com

Extensive genomic resources are available for this genus, including a chromosome-scale genome assembly for Primula veris, in which the S-locus is a ~ 260 kb region containing five genes (CCMT, GLOT, CYPT, PUMT, KFBT)12,17.
Source: Nature.com

"Related Reading X chromosome turned off in male cancers tooCopyright © 2022 scienceboard.
Source: The Science Board

Mike Adams: Natural News, “everyone’s favorite über-quack #1 anti-science website”— “even the quacks think he’s a quack” Genetic Literacy Project Center for Food Safety: Legal swat team of the anti-GMO and anti-pesticide movements Genetic Literacy Project Most Popular ‘Their joy knows no bounds’: Nigerian farmers welcome first harvest of disease-resistant genetically modified potatoes as a possible end to the ‘nightmare’ of late-blight potato disease Artificial wombs: The coming era of motherless births? ‘The Price of Immortality’: How long can gene therapy and cellular regeneration extend life? Part II: Jewish skeletal remains in a Norwich well — Do they undermine the controversial theory of ‘Jewish IQ’? How Freddie Mercury got his voice: It wasn’t his teeth A species of rat without the Y chromosome may foreshadow what might evolve in humans We’re more vulnerable to colds and flu in the winter.
Source: Genetic Literacy Project

Mapped reads were extracted per chromosome with Samtools45 and variant calling was performed with samtools mpileup and Varscan46.
Source: Nature.com

It suggested that a gene variant on chromosome 5 could be associated with cholesterol.
Source: SciTechDaily

The primary assumption of genomic selection is that genetic markers are closely linked on a chromosome with the causative loci that contribute to the trait of interest14.
Source: Nature.com

For the generation of a stable phage-resistant strain, an 8 kb DNA fragment encoding SspBCDE was integrated into the MG1655 chromosome to produce the MG1655-PT strain by using the pKOV-Kan gene replacement vector and lambda red-mediated homologous recombination38,39.
Source: Nature.com

The two transcriptional states could, therefore, be the result of differential chromosome conformation or compartmentalization, or mutually exclusive binding of specific regulators either to the promoter or to intron 1 through exon 4.
Source: Nature.com

In this study, the researchers used a set of chromosome single segment substitution lines derived from a cross between the weak-dormancy japonica rice cultivar Nipponbare and the strong-dormancy aus rice cultivar Kasalath to identify a gene, named as Seed Dormancy 6 (SD6), that contributes to rice seed dormancy.
Source: EurekAlert

Most human cells have two copies of each chromosome (ova and sperm are the exceptions, which both have just one copy).
Source: MSUToday

“We therefore have to find suitable conditions under which the cells will grow and divide their chromosome set in half.
Source: Eurasia Review

Its gene is located on chromosome 12q12-14 [3].
Source: Cureus

The rare condition, which affects one in every 15,000 children born in England, is caused by a defect on chromosome number 15 - and happens by chance.
Source: Daily Mail

The C9orf72 mutation features an expanded repeat of six “letters” of genetic code, GGGGCC, on chromosome 9, which may be duplicated between 65 and tens of thousands of times.
Source: UF Health News

We use block jackknife strategy (taking-one-chromosome-out)26 for error bar calculation of Sudan_Kadruka1_4000BP ‘s location on the PCA.
Source: Nature.com

Structural studies have provided insight into the mechanisms of DNA damage signaling at DNA double-strand breaks, and genomic approaches have revealed the origins of oncogenic chromosome aberrations resulting from such lesions.
Source: EurekAlert

Later, an autopsy report revealed their daughter had an extra 13th chromosome.
Source: ProPublica

Zink’s team isolated mitochondrial DNA (mtDNA)—the small circular chromosome in mitochondria that is inherited maternally—from the mummy’s tooth and from DNA samples provided by the proposed living relatives.
Source: The Scientist

Future studies might look at other forms of genetic variation, such as larger deletions or rearrangement of chromosome segments, says canine geneticist Adam Boyko at Cornell University in Ithaca, New York.
Source: Nature.com

Recommended Reading Angelman is most often caused by a de novo deletion of a region of the maternally inherited chromosome 15 containing the UBE3A gene.
Source: Angelman Syndrome News

" Starring: David Duchovny, Gillian Anderson, Mitch Pileggi Creator: Chris Carter Year: 1993 Rating: TV-14 Rotten Tomatoes Score: 74% Y: The Last Man FX on Hulu/YouTube When every living mammal with a Y chromosome mysteriously dies within a short time frame, the world is irrevocably changed.
Source: Looper

An efficient recombination system for chromosome engineering in Escherichia coli.
Source: Nature.com

When we sequenced a bunch of dogs and a bunch of wolves we used that to then search for mutations in the dog genome that only dogs had and we came out with a really nice hot spot of mutations on chromosome number six in the dog genome, and that's what's highlighted here.
Source: 60 Minutes CBS News

In HGPS, there is a tiny change in a gene on chromosome 1 that codes for the protein lamin A.
Source: Verywell Health

Single-cell analyses of chromosome structure in fixed cells4,13,14,15, chromosome tracing experiments16,17,18,19, in vitro9,10,20 and live-cell21 measurements of CTCF and cohesin dynamics, and polymer simulations6,15,22, as well as live-cell imaging of chromosomal locations and nascent RNA23,24, all suggested that TADs and CTCF loops are dynamic structures whose temporal evolution might be governed by the kinetics of loop extrusion25.
Source: Nature.com

agr dysfunction affects staphylococcal cassette chromosome mec type-dependent clinical outcomes in methicillin-resistant Staphylococcus aureus bacteremia.
Source: Nature.com

It's a rare genetic metabolic lysosomal discharge disorder caused by a mutation in the CTNS gene on the chromosome 17P13, which results in an abnormal accumulation of the amino acid cysteine in various organs and tissues throughout the body.
Source: Battling Cystinosis: Perspectives from a Doctor and a Patient Turned Advocate | Insights Holland & Knight

Distribution of chromosome length variation in natural isolates of Escherichia coli.
Source: Nature.com

When patients with undiagnosed or uncertain dysplasia or dysmorphism come to us, we offer karyotying first with or without chromosome microarray analysis.
Source: News-Medical.Net

"Related Reading X chromosome turned off in male cancers tooSome male cancers of diverse subtypes activate the gene responsible for shutting down gene expression of the X chromosome, Xist, and display features.
Source: The Science Board

“We see very few indels, and because we’re not making double-stranded breaks, you don’t have to worry about chromosomal rearrangements or large-scale chromosome arm deletions,” Abudayyeh says.
Source: MIT News

Lastly, 14 features corresponded to architectural properties of genes or transcripts such as the number of exons, guanine–cytosine (GC) content, chromosome number, the number of alternate transcripts and the length of the gene and mature transcripts (Supplementary Table 2).
Source: Nature.com

Hot spot: How the short arm of chromosome 16 is configured could explain why different types of genetic variants there converge on the same outcome.
Source: Spectrum Autism Research News

Genetics key to determine whether people can go grow beards The chromosome that determines whether a mammal is male or not is disappearing.
Source: indy100

image: Researchers report that in each organism, longer chromosome arms are always wider.
Source: EurekAlert

It would require taking the genome of the mammoth’s closest living relative – an Asian elephant – and introducing all the relevant changes (synthesising a whole chromosome is an incredibly arduous process and has not yet been performed in an animal; a woolly mammoth had twenty-nine pairs of chromosomes).
Source: Big Think

The first was gene variants found in a chromosome site called WNT7B.
Source: Study Finds

(For comparison, a single human chromosome contains between 50 million and 260 million bases.
Source: The Daily Beast

Mike Adams: Natural News, “everyone’s favorite über-quack #1 anti-science website”— “even the quacks think he’s a quack” Genetic Literacy Project Center for Food Safety: Legal swat team of the anti-GMO and anti-pesticide movements Genetic Literacy Project Most Popular ‘Their joy knows no bounds’: Nigerian farmers welcome first harvest of disease-resistant genetically modified potatoes as a possible end to the ‘nightmare’ of late-blight potato disease Artificial wombs: The coming era of motherless births? ‘The Price of Immortality’: How long can gene therapy and cellular regeneration extend life? Part II: Jewish skeletal remains in a Norwich well — Do they undermine the controversial theory of ‘Jewish IQ’? Part II: Viewpoint — Kenyan protestors aggressively promote disinformation in campaign to scuttle GM crop imports and cultivation How Freddie Mercury got his voice: It wasn’t his teeth A species of rat without the Y chromosome may foreshadow what might evolve in humans We’re more vulnerable to colds and flu in the winter.
Source: Genetic Literacy Project

We also used data from single-cell RNA sequencing studies of uveal melanoma42 and breast cancer41, in which chromosome copy number variations were used to infer clonal structure, and a study of acute myeloid leukaemia (AML) that used single-cell DNA sequencing24.
Source: Nature.com

At the PARP1 locus on chromosome 1, a tightly linked block of around 30 variants (29 in the 95% credible set from fine-mapping; Supplementary Table 6) with an alternate allele frequency (AAF) of 0.
Source: Nature.com

The locus with the strongest concordant effect on both the risk of BD and intelligence was in MIR2113 on chromosome 6 (rs1487445, conjFDR = 7.
Source: BMC Medicine BMC Medicine

In babies with Down Syndrome, the extra chromosome is stuck to another chromosome.
Source: News-Medical.Net

Due to the frequency of localization of guanidine-rich DNA sequences, computational calculations have predicted that the human genome contains approximately 376,000 potential putative G-quadruplex forming sequences, mainly at the end of the chromosome called telomeres.
Source: EurekAlert

The fire ant social chromosome supergene variant Sb shows low diversity but high divergence from SB.
Source: Nature.com

Left to right, examples of Pearson’s correlation matrices showing plaid-like chromosome compartments; saddle plots showing overall compartment strength (A-A: bottom right; B-B: top left); contact matrices showing TADs along the diagonal; aggregate domain analysis (ADA) showing all TADs; ADA showing TADs with downregulated YY1 ChIP-seq signals; contact matrices showing cohesin loops off the diagonal; and APAs showing overall loop intensity for cohesin loops.
Source: Nature.com

Image by Daron Herbert Modern horse populations demonstrate extremely low genetic diversity on the male Y chromosome, driven largely by breeder strategies, according to researchers.
Source: Horsetalk

5 Mb region overlapping the major histocompatibility complex class III (MHC-III) region on chromosome 6 that showed depleted genetic variation in the Anatolian EF population (Fig.
Source: Nature.com

ochotense, by its broader leaves and larger whitish perianth and diploid chromosome numbers.
Source: Nature.com

During counselling, parents were told that additional findings from GW-NIPT are all chromosome aberrations other than trisomies 21, 18 and 13.
Source: Nature.com

Association of the folded chromosome with the cell envelope of E.
Source: The Tonight Show Starring Jimmy Fallon

Doom’s plot is simple but the writers tried to make it smart with chromosome talk, some technobabble, and minute changes from its source, which is Aliens and not Doom; it’s a trainwreck.
Source: Voices From The Balcony

In 2010 scientists at JCVI unveiled the world’s first completely synthetic lifeform – a micro-organism derived from a synthetic chromosome made up of four chemicals and designed using a computer.
Source: New Atlas

For example, one locus on chromosome 2 is in a gene for the protein fibulin-3.
Source: University of Alabama at Birmingham

No scruff there!Whatever the differences between Zuckerberg and Bankman-Fried, they share the attribute of a Y chromosome and this affords them fashion options not open to women.
Source: Los Angeles Times

8 enrichment in sperm (right y axis; 1-kb windows) along chromosome 1.
Source: Nature.com

The reason may have more to do with the tumor’s aneuploidy status—the amount of extra chromosome gained or lost in a tumor.
Source: Inside Precision Medicine

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