10a)111; (3) identifying the last nucleotide incorporated by Pol II: we used the Python script mNET_snr (https://github.
Source: Nature.com
Secondly, a family-based association test was used to screen SNPs (single nucleotide polymorphisms) of vitamin D metabolic and functional pathway genes associated with vitamin D deficiency.
Source: Medical Dialogues
The other three are single nucleotide polymorphisms; ApaI and BsmI located in intron 10, and TaqI in extron 11, which don't change the amino acid sequence but they may decrease 1,25-dihydroxy vitamin D intracellularly or the VDR mRNA stability [19].
Source: Cureus
To track bacteria within-participant we mapped reads to reference genomes and defined high-level sequence clusters using popPUNK-17 and single nucleotide polymorphism (SNP)-clusters as isolates with whole-genome SNP distance ≤5.
Source: Nature.com
…
In extreme environments, microorganisms regulate the expression of a series of biofilm-forming genes through QS, nucleotide second messenger-based signaling, etc.
Source: Best They Can Do Is Start Again Science 2.0
4 µM each dNTP (New England BioLabs), 10 µM dithiothreitol (Thermo Fisher Scientific), 40 µM random heptamers with two 3′-terminal phosphorothioated nucleotide bonds (Integrated DNA Technologies) and 1 μM SYTO 9 (Thermo Fisher Scientific).
Source: Nature.com
Clade 1, also referred to as the Congo Basin clade, caused close to 10% mortality, while clade 2a, also called the West African clade, with 95% nucleotide sequence similarity, caused less than 1% mortality.
Source: News-Medical.Net
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences.
Source: Nature.com
If that preliminary analysis comes up short, investigators may analyze more than a half-million DNA single nucleotide polymorphisms, or SNPs, in the search for possible distant relatives of a suspect, Fox News reported.
Source: New York Post
“In previous research conducted using PacBio’s technology, HiFi sequencing detected more than two-fold structural variants and 200,000 more single-nucleotide variants than short-read sequencing,” Jonas Korlach, PhD, chief scientific officer at PacBio, said in a company press release.
Source: AADC News
I always use the title of this movie when I need to remember the four nucleotide bases of DNA.
Source: kottke.org
“Another key DNA marker we examined were single nucleotide polymorphisms, which are single-based changes all throughout the genome that give us clues about their ancient history several thousands of years ago.
Source: KAIT
The conditional quantile-quantile (Q-Q) plots were generated to provide a visual pattern of enrichment in single nucleotide polymorphism (SNP) associations between BD and intelligence.
Source: BMC Medicine BMC Medicine
In bladder cancer, we tend to see more of point mutations, or single nucleotide changes, whereas in cholangiocarcinoma, we tend to see more fusions or rearrangements of FGFR2.
Source: OncLive
This method, ‘RATES’, incorporates cohort-level summary statistics (single-nucleotide polymorphism (SNP) effect sizes and their corresponding standard errors), along with allele frequency-based MDS components per study to assign a posterior probability that each sentinel variant effect would replicate in a sufficiently powered study.
Source: Nature.com
(a, b) Phenotype associations of the single nucleotide polymorphisms rs373836366 (a) and rs780772968 (b) from the Type 2 Diabetes Knowledge Portal.
Source: Nature.com
7%) identified in our cohort harbored single-nucleotide substitutions resulting in disease-causing missense mutations (Table 2).
Source: Nature.com
0%, and 10% in the amino acid sequence and the nucleotide (nt) sequence, respectively, and the J gene lacked SHMs.
Source: News-Medical.Net
Despite the development of new techniques leading to current claims of gene associations based on genome-wide association (GWAS, based on common single nucleotide polymorphisms, or SNPs), polygenic risk score (PRS), and copy number variant (CNV) studies, genes shown to cause “schizophrenia”—a questionable concept in and of itself—remain undiscovered.
Source: Mad In America Mad in America
Molecular identification of Allium ochotense and Allium microdictyon using multiplex-PCR based on single nucleotide polymorphisms.
Source: Nature.com
Minimap2: pairwise alignment for nucleotide sequences.
Source: Nature.com
The first man had a missense mutation in a part of his EXT1 gene, whereby a single nucleotide base was swapped for another, scrambling the encoded sequence for the protein.
Source: ScienceAlert
RELATED: Idaho murders: Police search for white Hyundai Elantra near murder scene If the traditional STR DNA analysis doesn't come up with a match in CODIS, then investigators can analyze more than half a million DNA single nucleotide polymorphisms, or SNPs, to identify possible distant relatives of the unknown suspect.
Source: FOX 6 Milwaukee
Deblur rapidly resolves single-nucleotide community sequence patterns.
Source: Nature.com
Large-scale studies of the germline causes of clonal haematopoiesis have used samples from the UKB and other large cohorts, but those studies have been limited mostly to clonal haematopoiesis phenotypes that can be assessed using single nucleotide polymorphism (SNP) array genotype data, such as mosaic chromosomal alternations (mCA) and mosaic loss of sex chromosomes4,7,8 (mLOX and mLOY).
Source: Nature.com
Genome-wide mapping of mutations at single-nucleotide resolution for protein, metabolic and genome engineering.
Source: Hindustan Times
A definition that covers nucleotide sequence data (DNA/RNA) and other omics information (transcriptomes, proteins and metabolites) resulting from using genetic resources will provide a future-proof solution,” Varshney adds.
Source: Mongabay-India
“Another key DNA marker we examined were single nucleotide polymorphisms, which are single-based changes all throughout the genome that give us clues about their ancient history several thousands of years ago.
Source: YubaNet
The nucleotide pGpp acts as a third alarmone in Bacillus, with functions distinct from those of (p) ppGpp.
Source: Nature.com
Complete nucleotide sequence of pSK41: evolution of staphylococcal conjugative multiresistance plasmids.
Source: Nature.com
The nucleotide pGpp acts as a third alarmone in Bacillus, with functions distinct from those of (p)ppGpp.
Source: Nature.com
Bacteria utilize stringent factors to metabolize the nucleotide alarmone guanosine tetra-/pentaphosphate, or (p)ppGpp, for stress adaptation.
Source: Nature.com
So, the name for the company comes from a view that every nucleotide is like one tile in the mosaic of life.
Source: Genetic Engineering & Biotechnology News
“Another key DNA marker we examined were single nucleotide polymorphisms, which are single-based changes all throughout the genome that give us clues about their ancient history several thousands of years ago.
Source: Futurity: Research News
Frequencies of deletion position were calculated using the number of reads with deletions at designated nucleotide position divided by the total reads with deletions.
Source: Nature.com
" If the traditional STR DNA analysis doesn't come up with a match in CODIS, then investigators can analyze more than half a million DNA single nucleotide polymorphisms, or SNPs, to identify possible distant relatives of the unknown suspect.
Source: Fox News
Next, expression quantitative trait locus (eQTL) analysis was used to identify genes that are regulated by single nucleotide polymorphisms (SNPs) derived from the GWAS.
Source: BMC Medicine BMC Medicine
We modified a DNA signal gate from a previous work to create a gate with an eight-nucleotide toehold on its 3′-end, with one strand labeled with a fluorophore and the other strand with a quencher (Supplementary Data 1)29.
Source: Nature.com
The Ontario deer lineage forms a very long branch with 76 conserved nucleotide mutations relative to ancestral SARS-CoV-2 (Wuhan Hu-1) and 49 relative to their closest common ancestor with other genomes in GISAID (as of March 2022).
Source: Nature.com
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences.
Source: Nature.com
The cyclic nucleotide-gated channel CNGC14 regulates root gravitropism in Arabidopsis thaliana.
Source: Nature.com
"Another key DNA marker we examined were single nucleotide polymorphisms, which are single-based changes all throughout the genome that give us clues about their ancient history several thousands of years ago," Lyons added in a university news release.
Source: UPI News
Dante Labs’ whole genome sequencing and whole exome sequencing tests can identify large structural variants, copy number variations, and single nucleotide polymorphisms.
Source: TexasSports.com
“In a nutshell, it looks at your 675,000 single nucleotide polymorphisms that are directly or indirectly associated with your endocannabinoid system,” says Len May, founder and CEO of Endocanna Health.
Source: Genetic Engineering & Biotechnology News
Wild-type cells were used as a control to distinguish MitoKO DdCBE-induced C:G-to-T:A single-nucleotide variants (SNVs) from natural background heteroplasmy, which was at 0.
Source: Nature.com
SSCG, single-copy genes; LCG, low-copy genes; MT, mitochondrial genes; PT, plastid genes; AA, amino acid sequences; NT, nucleotide sequences; NT12, codon 1st + 2nd positions; ASTRAL, coalescent tree inference method using ASTRAL; CONCAT, maximum likelihood tree inferred with IQ-TREE based on concatenated datasets; STAG, species tree inference using software STAG with low-copy genes (one to four copies); Original, original organellar nucleotide sequences; RNA Editing, organellar genes with RNA editing site modified.
Source: Nature.com
The nucleotide sequences obtained were edited with BioEdit software v.
Source: Parasites & Vectors Parasites & Vectors
Here, we employed 272 single nucleotide polymorphisms from 208 Mangifera indica accessions to explore whether the genetic structure of the Australian mango gene pool explained variation in trunk circumference, fruit blush colour and intensity.
Source: Nature.com
Scientists also assessed and compared other DNA markers, known as single nucleotide polymorphisms (SNPs), which are single-base molecule changes all throughout the genome.
Source: The Independent
Intraspecific nucleotide variation in Anopheles gambiae: New insights into the biology of malaria vectors.
Source: Nature.com
Finished libraries underwent 146 nucleotide paired-end Illumina sequencing on an Illumina Novaseq 6000 instrument.
Source: Nature.com
Between 30% and 60% of blood pressure is down to genetic factors, and over 1000 genetic single nucleotide polymorphisms, or SNPs for short, are associated with it.
Source: Neuroscience News
5% average nucleotide identity (ANI) cluster with MAGs of lower quality from separate samples of the same enrichment culture and sediments from which the enrichment culture was derived.
Source: Nature.com
Cas13 (formerly C2c2) effectors are RNA-guided RNA nucleases whose catalytic activity resides in two higher eukaryotic and prokaryotic nucleotide binding (HEPN) domains6,29.
Source: Nature.com
Quantifying transmissionTo quantify and compare transmission events between different settings, we used a single-nucleotide polymorphism (SNP) threshold-based approach (thresholds: 0, 1, 2, 5, 10, 20).
Source: Nature.com
Parasite species identity was confirmed via NCBI nucleotide BLAST.
Source: Nature.com
7) to homology reduce ResFinder ARG collection to 90% nucleotide identity, with query and target coverage thresholds of 0.
Source: Nature.com
Frequently, average nucleotide identity (ANI) thresholds are used to infer transmission, but these need to be adjusted to evolutionary rates of specific pathogens54.
Source: Nature.com
Genetic study was performed by PCR-RFLP for 15 single nucleotide polymorphisms (SNPs) belonging to DBP, CYP2R1, CYP27B14, CYP24A1 and VDR genes.
Source: Nature.com
qpure: A tool to estimate tumor cellularity from genome-wide single-nucleotide polymorphism profiles.
Source: Nature.com
Our BEAST analysis was robust to both different priors on the age of the ancient sample, and to different nucleotide substitution models (Extended Data Fig.
Source: Nature.com
“Another key DNA marker we examined were single nucleotide polymorphisms, which are single-based changes all throughout the genome that give us clues about their ancient history several thousands of years ago,” Lyons added in a university news release.
Source: The Wellsboro Gazette
6% (520/3,557) of resistance elements, including known resistance single nucleotide polymorphisms (SNPs) and mobile genetic elements, when compared with using standard pipelines on the set of 1,158 single-colony whole-genome sequences (Extended Data Fig.
Source: Nature.com
10), based on relative evolutionary divergence (Supplementary Data 3), average amino acid identity, and average nucleotide identity (Supplementary Data 4).
Source: Nature.com
Accordingly, we reprocessed 1,162 ancient western Eurasian genomes (mostly high-density single-nucleotide polymorphism (SNP) scans; Methods) through a uniform bioinformatic pipeline, thereby mitigating potential processing artefacts, and grouped these samples into 18 distinct ancient populations that existed before and after documented Holocene admixture events based on their archaeological and genetic relationships (Fig.
Source: Nature.com
“In previous research conducted using PacBio's technology, HiFi sequencing detected more than two-fold structural variants and 200,000 more single-nucleotide variants than short-read sequencing,” Jonas Korlach, chief scientific officer at PacBio, said in a statement.
Source: LabPulse
Bars in each tree scaled to nucleotide substitutions per position, respectively.
Source: Nature.com
Cloning and expression of the mouse pgk-1 gene and the nucleotide sequence of its promoter.
Source: Nature.com
Oxytocin receptor single nucleotide polymorphism predicts atony-related postpartum hemorrhage1.
Source: 2 Minute Medicine
These data sets included results of whole-genome sequencing, which analyzes the entire genome, and single-nucleotide polymorphism arrays, which detect a subset of the variation in a genome.
Source: Neuroscience News
For major depression we used genome-wide significant single nucleotide polymorphisms (SNPs) as instruments7 (Source Data).
Source: Nature.com
The data generated for the Gough’s and Kendrick’s Cave individuals contains 506,151 and 476,347 single nucleotide polymorphisms (SNPs) respectively, overlapping the ‘1240k’ SNP panel45,46 informative of the genetic relationships amongst ancient and present-day humans.
Source: Nature.com
Oxytocin receptor single nucleotide polymorphism predicts atony-related postpartum hemorrhage1.
Source: 2 Minute Medicine
In previous research conducted using PacBio’s technology, HiFi sequencing detected more than two-fold structural variants and 200,000 more single-nucleotide variants than short-read sequencing.
Source: Labiotech.eu
A genome-wide association study was performed to look for novel single nucleotide variants associated with the characteristics identified in the study cohort.
Source: Monash University
The Genetic Structure of Ocular DiseaseA meaningful genetic structure within the diseases was found in the genetic correlation of common single nucleotide polymorphisms (SNPs) which allowed investigators to identify the genetic correlations between AMD, DR, and glaucoma.
Source: MD Magazine
Moreover, 129 vMAGs were linked to all 28 featured Actinobacteria MAGs from High S samples, potentially due to conserved nucleotide frequencies.
Source: Nature.com
“Another key DNA marker we examined were single nucleotide polymorphisms, which are single-based changes all throughout the genome that give us clues about their ancient history several thousands of years ago.
Source: EurekAlert
vastatrix’, by far the richest classical Rickettsiales described so far in terms of amino acid biosynthesis potential, can only synthesize 15 amino acids and lacks the genetic potential for de novo nucleotide biosynthesis (Fig.
Source: Albuquerque Business First The Business Journals
Alternatively, deep metagenomic sequencing can reveal nucleotide-level variation for many species of interest13, shedding light on strain-level dynamics in microbiomes.
Source: Nature.com
SNV, single nucleotide variant.
Source: Nature.com
Visitors also search for:
annotation in a sentence
paradigm in a sentence
resolution in a sentence
commemorate in a sentence
perish in a sentence